Improving cis-regulatory elements modeling by consensus scaffolded mixture models
نویسندگان
چکیده
منابع مشابه
CisModule: de novo discovery of cis-regulatory modules by hierarchical mixture modeling.
The regulatory information for a eukaryotic gene is encoded in cis-regulatory modules. The binding sites for a set of interacting transcription factors have the tendency to colocalize to the same modules. Current de novo motif discovery methods do not take advantage of this knowledge. We propose a hierarchical mixture approach to model the cis-regulatory module structure. Based on the model, a ...
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ژورنال
عنوان ژورنال: Science China Information Sciences
سال: 2011
ISSN: 1674-733X,1869-1919
DOI: 10.1007/s11432-011-4374-9